These medications, commonly prescribed for nonpsychiatric conditions, have the potential to interact with antidepressants, masking or diluting their effectiveness. This highlights how interconnected our treatments can be.
Tag: Inflammation and Depression
L-Methylfolate: A Potential Boost to Antidepressant Efficacy
The evidence shows that patients receiving 15 mg/day of LMF for 30 days exhibited significantly greater reduction in Hamilton Depression Rating Scale (HDRS-17) scores and higher response rates compared to the placebo group. Additionally, a 12-month open extension trial indicated that 60% of initial non-responders eventually achieved remission with no serious adverse events.